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Crinum Latifolium: Traditional Vietnamese Herb Shows Great Promise for Prostate & Ovarian Health

 

Traditional Vietnamese Herb Now Available in the U.S.

 

Crinum LatifoliumOne of Vietnam's most potent and effective medicinal herbs for prostate and ovarian health, Crinum Latifolium, has recently come into the spotlight. Used traditionally for longevity, Crinum was so revered in Vietnam, that it was reserved only for royalty, commonly referred to as the "Medicine for the King's Palace" and the "Royal Female Herb." These traditional nicknames highlight one of Crinum's most unique aspects - its ability to target both prostate and ovarian health. As clinicians well know, it is quite unusual for an herb to be effective for both of these male and female specific organs, but Crinum appears to be effective for both. Crinum's benefits have also been reported to extend well beyond prostate and ovarian health.*

What is Crinum latifolium’s relationship to Benign Prostatic Hyperplasia and Cancer?

 

There are over 500 successful case histories using Crinum for BPH. After seven years of research, the International Hospital in Vietnam reported that 92.6 percent of BPH patients had good results using Crinum (confirmed by measurements of prostate size and clinical evaluations by urologists).1

 

The doctors used the extract for 21-day cycles, with 7 days off in between. They reported no side effects and no lethal level in animals (meaning incredible safety). One of the patients in the study was a 72year-old man who had suffered from BPH symptoms for 3 years, often waking up 4-5 times per night with difficult urination. He was evaluated at the International Hospital in Vietnam and diagnosed with BPH with prostate dimensions of 4.1, 5.4 and 4.8 cm, with a weight of 53 grams. Previously, he had been advised to have his prostate removed, but because of a hypertensive condition, he tried a Crinum protocol instead. After only three, 21-day cycles of treatment, his prostate dimensions reduced to 2.9, 4.2 and 3.6, with a weight of just 22 grams. All his symptoms resolved and he reported feeling healthy.1  The National Health Committee declared Crinum to be the most promising area of research for the treatment of BPH.

 

In another Vietnamese study published in 2002, 158 Benign Prostatic Hyperplasia (BPH) patients were given a Crinum-based herbal preparation twice daily. After 64 days, patients were evaluated by clinical and ultrasound examinations. Researchers found that prostate size returned normal in 154 patients. They noted an incredible 97% success rate. A three-year follow up confirmed a high rate of long-term success for those patients who completed therapy.2

 

In 2001, a Vietnam Pharmaceutical Corporation published their findings that aqueous extracts from Crinum latifolium leaves from Vietnam showed in vitro and in vivo T-lymphocyte activation (Tram, et al., 1999) and retarded growth of chemically induced tumors (sarcomas) in rats (Tram et al., 2000).3

 

In yet another recent report from the Vietnamese Central State News Agency from September 2005, it was reported that “Crinum latifolium extract has a very good therapeutic effect on benign hyperthrophy of prostate (BHP)” based on the National Institute of Traditional Medicine of Ho Chi Minh City, and the Institute of Aging Disorders of Hanoi who tested Crinum in a large number of patients (627 patients) with BHP. The results showed a 33-93% reduction in urinary symptoms. 90% of the tested patients achieved a reduction in prostate size. Among them a significant number of patients achieved a normalization of prostate size and urinary health after three months of therapy. There was no significant adverse reactions noted.4

 

References:

 

  1. Crinum latifolium, a promising and highly effective treatment for BPH, health and life. The Journal of Health Ministry of Vietnam, December 20, 2002, N 207.
  2. Doan Thu Nhu. Crinum Latifolium in treatment of Benign Hypertrophy of prostate and cancers. Journal of Health and Life of Vietnamese Health Ministry, December 10, 2002, N 148.
  3. Nguyen Thi Ngoc Trama, Maya Mitovab. GC-MS of Crinum latifolium L. Alkaloids, Zeitschrift für Naturforschung B. (A Journal of Chemical Sciences). 57c, 239D242 (2002); received October 2/November 29, 2001
  4. Crinum latifolium extract has a very good therapeutic effect on benign hyperthrophy of prostate (BHP). Vietnamese central state news agency September 22, 2005,

 

Additional Published Research:

 

A novel in vitro and in vivo T-lymphocyte activating factor in Crinum latifolium (L.) aqueous extracts

 

NG. TH. NG. TRAM, E. ZVETKOVA*, E. NIKOLOVA*, E. KATZAROVA*,

G. KOSTOV**, I. YANCHEV***, O. BAICHEVA*** EXPERIMENTAL PATHOLOGY AND PARASITOLOGY, 3/1999 Bulgarian Academy of Sciences

 

Abstract

 

The antitumour activity of Crinum latifolium (L.) hot aqueous extracts has been used in Vietnamese and Chinese traditional medicine. In this study we report the possibility to enhance in vitro and in vivo cell (nuclear-, nucleolar-) activation – to blast cell proliferation of human and mouse peripheral blood T-lymphocytes by using Vietnamese Crinum latifolium (L.) cold/hot water extracts (decoctions). For this purpose human peripheral blood mononuclear cells (PBMCs) from healthy donors were obtained and cultured in supplemented RPMI 1640 containing (3:1) a cold/hot aqueous extract from Crinum latifolium (L.) – Vietnam.

 

Adherent and nonadherent cells that represent stimulated/effector T-cells were examined cytochemically for DNP, RNP and cationic (basic) proteins and by the immunocytochemical methods for CD3+T-, CD4+T- and CD8+T- cell verification. The results obtained showed that cold/hot water plant extract (decoction) can efficiently stimulate in vitro human T-lymphocytes activating especially cell-mediated immune response of CD4+T lymphocytes (T-helper cells): as early as 24 hours of human PBMCs cultivation in the presence of plant extract, 20% costimulation of T-helper cells (CD4+T-cells) was evaluated. The same water extract/decoction applied in vivo – per os, using healthy Balb/c mice, has the capacity to induce lymphocytosis and a strong lymphocyte activation – to lymphoblasts including, in the peripheral blood of experimental animals. Since some Amaryllidaceae alkaloids like ambelline, 1,2-β-epoxyambelline, lycorine, lycorine-1-O-β-D-glucoside etc., have been previously showed as active molecules with cytotoxic and immunostimulative properties, we presume their and other biologically active substances capacity to induce in vitro and in vivo T-lymphocyte activation and blast transformation comparable to the in vitro mitogenic effects of the well known lectin Con A. This could be of practical importance in the field of phytopharmacology – in the treatment of some cases of immunodeficiency as cancer,leukaemias and AIDS.

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